《植物生理学报》 2010, 46(7): 643-648

蛋白质内含肽的研究及应用进展

韦静宜, 宋洪元*, 李成琼, 王小佳, 司军, 任雪松

西南大学蔬菜重点实验室, 重庆400715

通信作者：宋洪元；E-mail: yuahs@sohu.com；Tel: 023-68250974

摘　要：

内含肽的发现与研究只经过短短的20年, 但已在各个生物领域展现出应用潜力。本文阐述了蛋白质内含肽的相关概念、种类、分布、结构、功能和自我剪接机制。分析了内含肽在当前生物技术领域中的应用情况以及存在的优点和局限性, 最后就内含肽的应用前景进行了展望。

关键词：内含肽;自我剪接机制; 研究及应用

收稿：2010-02-01   修定：2010-04-13

资助：国家自然科学基金(30771462)、重庆市自然科学基金(2007BB1358)和西南大学博士启动基金(SWUB2008021)。

Research and Application Advancement of Intein

WEI Jing-Yi, SONG Hong-Yuan*, LI Cheng-Qiong, WANG Xiao-Jia, SI Jun, REN Xue-Song

Key Laboratory of Olericulture, Southwest University, Chongqing 400715, China

Corresponding author: SONG Hong-Yuan; E-mail: yuahs@sohu.com; Tel: 023-68250974

Abstract:

In spite of only 20 years period for discovery and investigation of intein, its potential application value in biological research has been revealed. This paper reviewed the related concepts, types, distribution, configuration, functions and the self-splicing mechanism of intein. The applications of intein in biotechnology area were analyzed advantages and limitation. The application direction for the intein in future was also suggested.

Key words: intein; self-splicing mechanism; research and application